Antimicrobial Resistance of Salmonella enterica Serotype Typhi in Dakar, Senegal

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Abstract
SIR—Typhoid fever, a systemic infection due to Salmonella enterica serotype Typhi, remains an important public health problem in many countries in the world [1]. In developed countries, sporadic typhoid fever is generally reported in travelers returning from an area of endemicity, whereas, in developing countries, particularly in Africa and Southeast Asia, this disease may be associated with high incidences of morbidity and mortality [1, 2]. In developing countries, poor sanitary conditions appear to be the main risk factor. However, with the emergence of antimicrobial resistance, developing countries are facing alarming problems with treating this condition efficiently [1]. Antimicrobial resistance affects mainly Asia, where nalidixic acid–resistant strains have already been reported in many countries, but resistance has also spread progressively across Africa [1].