Blood lymphocytes in acute lymphoid leukaemia in remission and in relapse. Predictive value of electrophoretic mobility and refringence.

  • 10 September 1975
    • journal article
    • Vol. 23  (7) , 283-90
Abstract
Blood lymphocytes were studied during the evolution of acute lymphocytic leukaemia, including remissions and relapses, under chemotherapy and immunotherapy. Lymphoblasts migrate as a uniform population and have a mean electrophoretic mobility of 1.04 mum-sec-1. V-1cm. These lymphoblasts are also refringent. The relapse seems to be preceded by a slowing of the electrophoretic mobility of fast cells and a rise in the percentage of refringent lymphocytes.

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