The Effect of Arsenic on Inflammation

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Abstract
There is clinical and experimental evidence that an amount of arsenicals which will not produce lesions on normal skin will markedly increase the severity of a quantitated, induced, bacterial infection. It is also known that suppression of early inflammation increases the severity of bacterial infections. Art experimental model is presented in which arsenic is shown to prevent one type of early inflammation. It is proposed that arsenic damages enzymes of inflammation which are active before the cellular phase occurs.