Basophil Histamine Release and Humoral Changes during Immunotherapy
- 28 April 1982
- Vol. 37 (3) , 187-190
- https://doi.org/10.1111/j.1398-9995.1982.tb01895.x
Abstract
An in vitro pilot study was performed to determine whether human basophil cell-bound specific IgE was correlated to serum-specific IgE and to basophil cell sensitivity during immunotherapy with a well-documented treatment. The findings showed a clear dissociation between the 3 parameters, which is in contrast to the situation before hyposensitization and to a study in a comparable group of non-hyposensitized patients, where highly significant correlations were observed. Investigations are in progress to clarify whether the dissociation is involved in the clinical improvement.Keywords
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