Conformation takes precedence over sequence in adeno-associated virus DNA replication.
Open Access
- 1 July 1984
- journal article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 4 (7) , 1416-1419
- https://doi.org/10.1128/mcb.4.7.1416
Abstract
Deletion of an 11-base symmetrical sequence in the inverted terminal repetition of the adeno-associated virus 2 genome inhibits DNA replication. Substitution of either an 8- or a 12-base symmetrical sequence unrelated to the original 11-base sequence restores DNA replication.Keywords
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