Measurements of Some Radiobiological and Physical Properties of Neutrons Produced by a 4-MV Van de Graaff Accelerator
- 1 February 1982
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 89 (2) , 227-237
- https://doi.org/10.2307/3575769
Abstract
Measurements were made of the energy spectrum and radiobiological properties of neutrons generated by 4-MeV deuterons on a thick beryllium target. The mean neutron energy determined, using emulsion techniques, was 3.0 MeV. The survival curves for 2 cell lines (V79 379A Chinese hamster lung cells and WHFIB murine fibrosarcoma) irradiated with neutrons had a small shoulder. V79 cells were capable of recovering from the sublethal damage this shoulder represented. The oxygen enhancement ratio was reduced from 3.2 and 2.7 for the 2 cell lines irradiated with X-rays to 1.6 and 1.5, respectively, following neutron irradiation. The RBE (relative biological effectiveness) for tumor cells irradiated in vivo or in vitro and assayed in vitro were in good agreement with each other. However, the RBE for tumor growth delay was higher than that for tumor cell survival.This publication has 1 reference indexed in Scilit:
- The Effect of a Change in Radiation Quality on the Ability of Electron Affinic Sensitizers to Sensitize Hypoxic CellsInternational Journal of Radiation Biology, 1976