The Response of Newborns to Succinylcholine and d -Tubocurarine

Abstract
The durations of action of succinylcholine and d-tubocurarine in newborns and adults were compared. Patients were given similar doses on the basis of body surface area, d-tubocurarine, 4 mg/m2, and succinylcholine, 40 mg/m2. Duration of action was evaluated by observing muscle response to nerve stimulation. We found little difference between the durations of action of succinylcholine in newborns and adults. Newborns, on the other hand, were more sensitive to d-tubocurarine than adults.

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