Long‐term botulinum toxin treatment increases employment rate in patients with cervical dystonia
- 19 August 2005
- journal article
- clinical trial
- Published by Wiley in Movement Disorders
- Vol. 20 (12) , 1604-1609
- https://doi.org/10.1002/mds.20670
Abstract
We examined the impact of cervical dystonia (CD) and long‐term botulinum toxin (BTX) treatment on employment status. Data on employment status at onset of CD, at initiation of BTX treatment, and at evaluation of long‐term treatment were obtained from 62 CD patients aged 31–66 years (median, 53 years; 61% females) who had been treated for a median of 5 years (range, 1.5–10 years). The employment rate fell from 84% at the onset of CD to 47% before initiation of BTX treatment. With long‐term BTX treatment, 72% of those who worked at the initiation of treatment stayed employed, and 67% of those on sick leave returned to work. A younger age and a higher level of education increased the probability of being employed and avoiding disability benefits. Among those who were younger than 55 years at evaluation of BTX treatment (n = 40), the employment rate increased from 47% to 65% with treatment, and among the male patients, it reached the level of the general population (86%). About half of the 34% who received disability benefits did so already before the BTX treatment was initiated. © 2005 Movement Disorder SocietyKeywords
This publication has 16 references indexed in Scilit:
- The course of cervical dystonia and patient satisfaction with long‐term botulinum toxin A treatmentEuropean Journal of Neurology, 2005
- Efficacy of pharmacological treatment of dystonia: evidence‐based review including meta‐analysis of the effect of botulinum toxin and other cure optionsEuropean Journal of Neurology, 2004
- Long‐term efficacy of botulinum toxin A in treatment of various movement disorders over a 10‐year periodMovement Disorders, 2002
- What are the determinants of quality of life in people with cervical dystonia?Journal of Neurology, Neurosurgery & Psychiatry, 2002
- Long-term treatment of cervical dystonia with botulinum toxin A: efficacy, safety, and antibody frequencyZeitschrift für Neurologie, 1999
- Spasmodic Torticollis—A Multicentre Study on Behavioural Aspects II: Signs, Symptoms and CourseBehavioural Neurology, 1996
- Spasmodic Torticollis—A Multicentre Study on Behavioural Aspects III: Psychosocial Changes and CopingBehavioural Neurology, 1996
- Markov Chains: IntroductionPublished by Elsevier ,1994
- Natural History of Adult-Onset Idiopathic TorticollisArchives of Neurology, 1990
- Epidemiology of focal and generalized dystonia in Rochester, MinnesotaMovement Disorders, 1988