Uncertain Identity of Doxorubicin-Resistant MCF-7 Cell Lines Expressing Mutated p53
Open Access
- 20 September 2000
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 92 (18) , 1535-1536
- https://doi.org/10.1093/jnci/92.18.1535
Abstract
The doxorubicin (ADR)-selected human breast cancer cell line (MCF-7/ADR-RES) has been a useful model for a multidrug-resistant subline in cancer research. However, a recent letter to the Journal has alerted the scientific community about the finding that MCF-7/ADR-RES is not a MCF-7-derived cell line. This report led to a change of nomenclature from MCF-7/ADR-RES to NCI/ADR-RES (1).Keywords
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