A Common Polymorphism in SCN5A is Associated with Lone Atrial Fibrillation
- 1 January 2007
- journal article
- Published by Wiley in Clinical Pharmacology & Therapeutics
- Vol. 81 (1) , 35-41
- https://doi.org/10.1038/sj.clpt.6100016
Abstract
The cardiac sodium channel (SCN5A) is a target for the treatment of arrhythmias. We hypothesized that vulnerability to atrial fibrillation (AF) could be caused by genetic variation in SCN5A. We recru...Keywords
This publication has 41 references indexed in Scilit:
- Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillationHuman Molecular Genetics, 2006
- Heart Disease and Stroke Statistics—2006 UpdateCirculation, 2006
- Familial aggregation of atrial fibrillation in IcelandEuropean Heart Journal, 2006
- Relation of 97T Polymorphism in KCNE5 to Risk of Atrial FibrillationThe American Journal of Cardiology, 2005
- A Kir2.1 gain-of-function mutation underlies familial atrial fibrillationBiochemical and Biophysical Research Communications, 2005
- Identification of a KCNE2 Gain-of-Function Mutation in Patients with Familial Atrial FibrillationAmerican Journal of Human Genetics, 2004
- C825T polymorphism of the G-protein β3 subunit gene and atrial fibrillation: Association of the TT genotype with a reduced risk for atrial fibrillationAmerican Heart Journal, 2004
- An intronic mutation causes long QT syndromeJournal of the American College of Cardiology, 2004
- KCNQ1 Gain-of-Function Mutation in Familial Atrial FibrillationScience, 2003
- SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndromeCell, 1995