EFFECTS OF ALTERATIONS IN BODY TEMPERATURE ON PROPERTIES OF CONVULSIVE SEIZURES IN RATS
- 1 August 1948
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 154 (2) , 207-210
- https://doi.org/10.1152/ajplegacy.1948.154.2.207
Abstract
Characteristics of exptl. seizures were studied in rats whose body temps. were altered by exposure to extreme environmental temps. Seizure threshold was increased, seizure duration reduced and post-seizure recovery hastened by increased body temp., and all were conversely changed by decreased body temp. The data were adequately fitted by plotting the logarithm of each function against the reciprocal of absolute body temp. For seizure threshold the Q10 was found to be 1.6, for seizure duration 2.8, and for recovery 2. The possible significances of the findings are briefly discussed.Keywords
This publication has 6 references indexed in Scilit:
- PROPERTIES OF MAXIMAL SEIZURES, AND THEIR ALTERATION BY ANTICONVULSANT DRUGS AND OTHER AGENTSJournal of Neurophysiology, 1946
- THE EFFECT OF CELLULAR HYDRATION ON EXPERIMENTAL ELECTROSHOCK CONVULSIONSJournal of Neurophysiology, 1946
- OBSERVATIONS ON REFLEX RESPONSES DURING PROLONGED PERIODS OF HUMAN REFRIGERATIONArchives of Neurology & Psychiatry, 1941
- CONVULSIONS IN CHILDHOODJAMA, 1939
- ‘Master reactions’ and temperature characteristicsJournal of Cellular and Comparative Physiology, 1937
- The basis of the principle of the master reaction in biologyJournal of Cellular and Comparative Physiology, 1936