Recent advances and prospective researches on molecular epidemiology of dengue viruses
Open Access
- 1 January 1992
- journal article
- review article
- Published by FapUNIFESP (SciELO) in Memórias do Instituto Oswaldo Cruz
- Vol. 87 (suppl 5) , 133-136
- https://doi.org/10.1590/s0074-02761992000900021
Abstract
The determination of amino acid changes in the envelope protein by direct sequencing of either genomic RNA or PCR-amplified cDNA fragments provides useful informations for assessing the genetic variability and the geographic distribution of the actually most widespread dengue-2 serotype. The possible link of variations in the envelope protein-gene and virus virulence is discussed.Keywords
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