Experiments of the synthesis of tetracycline. Part V. Photocyclisation of ring B
- 1 January 1971
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- Vol. 12, 2193-2203
- https://doi.org/10.1039/j39710002193
Abstract
The ethylene acetal of 4-(2-formylbenzyl)-2phenylnaphtho[1,8-bc]furan-5-one (III; XY = O) has been cyclised under acid-catalysed photolytic conditions to 12-ethylenedioxy-6α,7,12,12aα-tetrahydro-1-phenylnaphthaceno[1,12-bc]furan-6-one (V; XY = O·CH2·CH2·O). This method of establishing the linear tetracyclic carbon skeleton has been extended to dithio and monothio-acetals, and to the parent aldehyde (III; XY = O) itself.Keywords
This publication has 0 references indexed in Scilit: