Labelling of aromatic amino-acids stereoselectively with tritium in the β-methylene group: the stereochemistry of hydroxylation in the biosynthesis of haemanthamine
- 1 January 1971
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 8,p. 415-416
- https://doi.org/10.1039/c29710000415
Abstract
Catalytic hydrogenation of acylaminocinnamic acids proceeds cis with high stereoselectivity and provides a route to aromatic amino-acids labelled stereoselectively with deuterium or tritium in the β-methylene groups; [βR-3H]- and [βS-3H]-tyrosine, prepared in this way, were used to show that a hydroxylation step in the biosynthesis of haemanthamine proceeded with retention of configuration.Keywords
This publication has 0 references indexed in Scilit: