Studies of Ferritin and a New Iron-binding Protein Found in the Intestinal Mucosa of the Rat

Publisher Website
Google Scholar
Abstract
Intestinal mucosa and liver tissues from adult rats were examined for ferritin in these studies. Starch gel electrophoresis of preparations of these tissues labeled in vivo with iron-59 were stained with amido black for protein, and radio-autographs were made of the gel slabs. Commercially obtained horse spleen ferritin was used as a reference standard. Results showed that intestinal mucosa contains ferritin with the same electrophoretic mobility as the alpha band of horse spleen ferritin as well as another iron-containing protein (MIBP). Liver preparations contained ferritin which corresponded to the beta band of horse spleen ferritin and did not contain MIBP. Both ferritins could be precipitated with rabbit antiferritin serum but MIBP could not.

This publication has 5 references indexed in Scilit: