EPIDEMIOLOGY OF SULFONAMIDE-RESISTANT MENINGOCOCCAL INFECTIONS IN A CIVILIAN POPULATION1

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Abstract
Foster, M. T. (Washington Univ. Medical Service, 1515 Lafayette St., St. Louts, Missouri 63104), E. Sanders and M. Ginter). Epidemiology of sulfonamide-reslstant meningococcal infections in a civilian population. Amer J Epidem 93: 346–353, 1971.—An outbreak of infections due to Group B, sulfadiazine-resistant meningococci occurred among residents of a well-circumscribed area within the city of Jacksonville, Florida. Distinguishing features of the outbreak were: lengthy duration; high fatality rate; geographic clustering of cases; and tendency for multiple cases to occur among related, crowded individuals. High rates of asymptomatic carriage of meningococci were found among individuals of low socioeconomic status residing in densely populated areas. High rate of carriage of the epidemic Group B, sulfonamide-resistant strain was found only in household contacts of cases. Low rate of carriage of meningococci and absence of the epidemic strains were noted among those of higher socioeconomic status residing in less densely populated areas of the city. Penicillin was of no value in elimination of meningococci from carriers or in prevention of disease.

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