Clusters containing different mobile dispersed genes in the genome of Drosophila melanogaster
- 1 January 1980
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 8 (6) , 1243-1258
- https://doi.org/10.1093/nar/8.6.1243
Abstract
Ten clones containing the actively transcribed mobile dispersed gene Dm255 and its flanking sequences were selected from the HindIII bank of the Drosophila melanogaster genome. The Dm225 sequences present in these clones were identical while the flanking sequences were different in all of the clones analysed. Four of them contained, in addition to Dm225, other DNA sequences binding high amounts of cytoplasmic poly(A) + RNA. The properties of these new genes are similar to those of Dm255: they are also actively transcribed, multiple in copies, scattered throughout the genome, and located at varying genome sites which also were scattered throughout the whole genome of D. melanogaster. Thus, different mobile dispersed genes often appear as closely apposing units forming gene clusters in the genome.Keywords
This publication has 14 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- Studies on the DNA Fragments of Mammals and Drosophila Containing Structural Genes and Adjacent SequencesPublished by Cold Spring Harbor Laboratory ,1978
- Repeated Gene Families in Drosophila melanogasterCold Spring Harbor Symposia on Quantitative Biology, 1978
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Isolation of Eukaryotic DNA Fragments Containing Structural Genes and the Adjacent SequencesScience, 1977
- Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.Proceedings of the National Academy of Sciences, 1975
- A freeze-squeeze method for recovering long DNA from agarose gelsAnalytical Biochemistry, 1975
- Localization of RNA from heat-induced polysomes at puff sites in Drosophila melanogaster.Proceedings of the National Academy of Sciences, 1975
- Interspersion of repetitive and nonrepetitive DNA sequences in the Drosophila melanogaster genomeCell, 1975
- Host specificity of DNA produced by Escherichia coli: Bacterial mutations affecting the restriction and modification of DNAJournal of Molecular Biology, 1966