Hemopoietic Growth Factors Regulate the Survival of Human Basophils in vitro
- 1 January 1992
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 97 (4) , 322-329
- https://doi.org/10.1159/000236140
Abstract
Human basophils were purified from normal peripheral blood, using density gradient followed by negative panning selection. We tested the effects of hemopoietic growth factors on the survival of these basophils in vitro. In the absence of exogenous factors, basophils (purity > 90%) decreased in number rapidly. At day 7 only 11% of the cells remained alive in cultures;Keywords
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