Metabolic control and future opportunities for growth regulation

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Abstract
The last 10 years have seen a significant expansion in the scope of attempts to manipulate the growth of animals (Buttery, Lindsay and Haynes, 1986). The expansion of interest has been driven by a number of factors, both economic and theoretical. At the economic level the need to develop energetically and economically efficient strategies of animal production has been coupled with a renewed awareness of the implications for human health of excessive intakes of saturated fats. Emphasis then has switched from the maximization of weight gain as an end in itself towards a need to promote protein deposition at any given intake and, at the same time, to reduce the fat content of meat and meat products. These twin objectives might be achieved by one of three strategies: the promotion of protein deposition alone, because at any given rate of weight gain this will tend to minimize the rate of fat deposition (the so-called repartitioning effect); the reduction of fat gain (an approach that has received particularly close attention by those concerned primarily with human obesity); or ideally the simultaneous promotion of protein accretion and depression of that of fat.