Synthesis of dimethyl 5, 5, 6, 6 (2H4)‐2‐oxoheptylphosphonate, a deuterium labelled prostaglandin intermediate
- 1 April 1982
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 19 (4) , 491-501
- https://doi.org/10.1002/jlcr.2580190405
Abstract
The synthesis of the specifically labelled versatile prostaglandin intermediate 1b is described which involves the preparation of 2,2,3,3 (2H4)butyliodide 6b via homogenous catalytic deuteration of the acetylene 4. Examples for the preparation of prostaglandins and extensive spectroscopic data are included.Keywords
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