Zygosity Partitioning of Small Twin Samples
- 1 April 1985
- journal article
- research article
- Published by Cambridge University Press (CUP) in Acta geneticae medicae et gemellologiae: twin research
- Vol. 34 (3-4) , 167-174
- https://doi.org/10.1017/s0001566000004682
Abstract
When the Weinberg estimate of the proportion of monozygotic pairs is quite deviant from that in the source population, it is likely to be wrong because Weinberg's difference is much less stable than the zygosity proportions. A formula is proposed for the probability distribution of possible compositions of a small sample of twins based on sex concordance in the sample and zygosity proportions in the source population.Keywords
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