Palladium and Raney Nickel Catalyzed Methanolic Cleavage of Stable Borane−Amine Complexes
- 17 January 2001
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 3 (3) , 465-467
- https://doi.org/10.1021/ol006969+
Abstract
Palladium and Raney nickel were found to catalyze the methanolysis of borane−amine adducts. Hence, strongly complexed amines can now be liberated by simple treatment with Pd/C or Raney Ni in methanol. The method is applicable to primary, secondary, tertiary, and aromatic amines, and the mildness of the reaction conditions allows preservation of otherwise labile functional groups.Keywords
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