First synthesis of β-2′-deoxy[9-15N]adenosine
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 7,p. 595-597
- https://doi.org/10.1039/p19960000595
Abstract
We report the first synthesis of β-2′-deoxy[9-15N] adenosine: the last of the singly labelled 5N β-2′-deoxyadenosines to be synthesized. Using commercially available 5-amino-4,6-dichloropyrimidine and 2–10 equivalents of 15NH3, β-2′-deoxy[9-15N]adenosine has been constructed in four steps in good overall yield.Keywords
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