Antagonism of Veratrine by Calcium Ion in Monolayers of Stearic Acid
- 22 May 1959
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 129 (3360) , 1427-1428
- https://doi.org/10.1126/science.129.3360.1427
Abstract
Force-area diagrams for monolayers of stearic acid on Ringer's solution demonstrate a competition between veratrine and calcium for carboxyl groups of the films. The competition occurs at customary concentrations. Local anesthetics act quite differently. The interactions suggest those observed less directly in living cells and therefore indicate that such surface films may serve as models for the study of drug and ion effects.Keywords
This publication has 3 references indexed in Scilit:
- Local Anaesthetics. V. The Action of Local Anaesthetics on Monomolecular Layers of Stearic Acid.Acta Pharmacologica et Toxicologica, 1954
- On the Effect of Temperature on the Depolarization of Frog Nerve FibersActa Physiologica Scandinavica, 1951
- The mode of action of certain insecticides on the arthropod nerve axonJournal of Cellular and Comparative Physiology, 1947