THE FIBRINOGEN‐DEPENDENT PATHWAY OF PLATELET AGGREGATION*
- 1 June 1983
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 408 (1) , 556-566
- https://doi.org/10.1111/j.1749-6632.1983.tb23272.x
Abstract
Fibrinogen participates in platelet aggregation induced by ADP and this participation is receptor mediated. The role of fibrinogen in platelet function is not restricted to the ADP stimulus as the molecule may regulate aggregation induced by the direct interaction of the protein with a single, specific receptor system. Thus, a common fibrinogen-dependent mechanism leading to platelet aggregation is hypothesized.Keywords
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