catmap: Case-control And TDT Meta-Analysis Package
Open Access
- 28 February 2008
- journal article
- Published by Springer Nature in BMC Bioinformatics
- Vol. 9 (1) , 130
- https://doi.org/10.1186/1471-2105-9-130
Abstract
Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies may be helpful to increase the ability to detect association when effect sizes are modest. Although many software options are available for meta-analysis of genetic case-control data, no currently available software implements the method described by Kazeem and Farrall (2005), which combines data from independent family-based and case-control studies.Keywords
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