Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: Association with an attenuated CYP2B induction by phenobarbital
Open Access
- 4 June 2005
- journal article
- Published by Wiley in FEBS Letters
- Vol. 579 (17) , 3560-3564
- https://doi.org/10.1016/j.febslet.2005.05.028
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in MiceCancer Research, 2004
- Cytoplasmic Accumulation of the Nuclear Receptor CAR by a Tetratricopeptide Repeat Protein in HepG2 CellsMolecular Pharmacology, 2003
- Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbitalFEBS Letters, 2003
- Pathophysiological Factors Affecting CAR Gene ExpressionDrug Metabolism Reviews, 2003
- The role of hepatocyte RXRα in xenobiotic-sensing nuclear receptor-mediated pathwaysEuropean Journal of Pharmaceutical Sciences, 2002
- Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid LigandsJournal of Biological Chemistry, 2000
- Phosphorylation/Dephosphorylation Steps Are Crucial for the Induction of CYP2B1 and CYP2B2 Gene Expression by PhenobarbitalBiochemical and Biophysical Research Communications, 1999
- Differential regulation of cytochrome(s) P450 2B1/2 by phenobarbital in hepatic hyperplastic nodules induced by aflatoxin B1 or diethylnitrosamine plus 2-acetylaminofluorene in male F344 ratsToxicology and Applied Pharmacology, 1991
- Phenobarbital induction of cytochrome P-450 in normal and preneoplastic rat liver: comparison of enzyme and mRNA expression as detected by immunohistochemistry and in situ hybridizationCarcinogenesis: Integrative Cancer Research, 1987
- 1.5 Kb mRNA abundantly expressed in rat tumors encodes a 37 kilodalton proteinBiochemical and Biophysical Research Communications, 1985