Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225
Top Cited Papers
- 1 June 2001
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 144 (6) , 1169-1176
- https://doi.org/10.1046/j.1365-2133.2001.04226.x
Abstract
Background C225 is an antibody to the epidermal growth factor receptor (EGFR), and inhibits growth of various tumour cells. The antibody is currently being used as a therapeutic agent in several cli...Keywords
This publication has 35 references indexed in Scilit:
- The Biologic Effects of C225, A Chimeric Monoclonal Antibody to the EGFR, on Human Prostate CarcinomaJournal of Immunotherapy, 1996
- Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptorNature, 1995
- Antitumor Effects of Doxorubicin in Combination With Anti-epidermal Growth Factor Receptor Monoclonal AntibodiesJNCI Journal of the National Cancer Institute, 1993
- TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 miceCell, 1993
- Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammationCell, 1993
- Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.Genes & Development, 1991
- Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human SkinJournal of Investigative Dermatology, 1990
- Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal AppendagesJournal of Investigative Dermatology, 1984
- Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth CycleJournal of Investigative Dermatology, 1984
- Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.Proceedings of the National Academy of Sciences, 1983