The influence of food intake on the development of structural and functional adaptation following ileal resection in the rat.
Open Access
- 1 June 1975
- Vol. 16 (6) , 468-472
- https://doi.org/10.1136/gut.16.6.468
Abstract
The present study was undertaken to determine the influence of hyperphagia on the adaptive changes occurring in the rat jejunal mucosa as a result of intestinal resection. One group of resected rats was subjected to pair feeding with a sham-operated population, whilst another group was nourished ad libitum. The animals which ate ad libitum developed hypertrophy of the mucosa which was accompanied by increased glucose absorption in vivo without changes in enzyme levels. These alterations were much less pronounced in the pair-fed group of resected animals, a finding that indicates that the adaptive changes are at least partially influenced by increased luminal nutrition.Keywords
This publication has 6 references indexed in Scilit:
- The nutritive effect of glucose on teh structure and function of jejunal self-emptying blind loops in the rat.Gut, 1975
- [Function and structure of the intestinal mucosa after massive resection of the small intestine in dogs].1974
- Biochemical Changes in Intestinal Mucosa after Experimental Small Bowel by-Pass in the RatClinical Science, 1972
- Carbohydrate digestion and absorption after massive resection of the small intestine.1972
- Structural and functional changes following small intestinal resection in the rat.1967
- Intestinal hypertrophy following partial resection of the small bowel in the ratBritish Journal of Surgery, 1959