Capecitabine
- 1 November 2000
- journal article
- review article
- Published by Springer Nature in Investigational New Drugs
- Vol. 18 (4) , 355-363
- https://doi.org/10.1023/a:1006449315650
Abstract
Drug development has undergone rapid shifts inmethodology and the use of rationally derived agents which eithertarget specific tissues or molecules such as receptors orenzymatic sites. Capecitabine...Keywords
This publication has 29 references indexed in Scilit:
- Influence of the antacid Maalox on the pharmacokinetics of capecitabine in cancer patientsCancer Chemotherapy and Pharmacology, 1999
- Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer.Journal of Clinical Oncology, 1998
- Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissuePublished by Elsevier ,1998
- Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine.Journal of Clinical Oncology, 1998
- Tumor Selective Delivery of 5-Fluorouracil by Capecitabine, a New Oral Fluoropyrimidine Carbamate, in Human Cancer XenograftsBiochemical Pharmacology, 1998
- Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts.1998
- Computer-Assisted Design of New Drugs Based on Retrometabolic ConceptsSAR and QSAR in Environmental Research, 1998
- A Pilot Safety Study of Capecitabine, A New Oral Fluoropyrimidine, in Patients with Advanced Neoplastic DiseaseTumori Journal, 1996
- 5′-Deoxy-S-fluorouridine Increases Daunorubicin Uptake in Multidrug-resistant Cells and Its Activity Is Related with P-gp 170 ExpressionJapanese Journal of Cancer Research, 1994
- 5'-DFUR, A NEW ANTI-CANCER AGENT ACTIVATED SELECTIVELY IN TUMOR-CELLS .3. TISSUE DISTRIBUTION OF 5'-DEOXY-5-FLUOROURIDINE AND DERIVED 5-FLUOROURACIL IN TUMOR-BEARING MICE AND RATS1980