Novel mono- and di-DNA-enzymes targeted to cleave TAT or TAT-REV RNA inhibit HIV-1 gene expression
- 22 June 2001
- journal article
- Published by Elsevier in Antiviral Research
- Vol. 51 (2) , 127-139
- https://doi.org/10.1016/s0166-3542(01)00144-9
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Sequence specific cleavage of the HIV‐1 coreceptor CCR5 gene by a hammer‐head ribozyme and a DNA‐enzyme: inhibition of the coreceptor function by DNA‐enzymeFEBS Letters, 1998
- Targeted cleavage of HIV‐1 envelope gene by a DNA enzyme and inhibition of HIV‐1 envelope‐CD4 mediated cell fusionFEBS Letters, 1998
- Characterization of Several Kinds of Dimer Minizyme: Simultaneous Cleavage at Two Sites in HIV-1 Tat mRNA by Dimer MinizymesNucleic Acids Research, 1996
- Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint.Proceedings of the National Academy of Sciences, 1996
- Efficient hammerhead ribozyme-mediated cleavage of the structured heapatitis B virus encapsidation signalin vitroand in cell extracts, but not in intact cellsNucleic Acids Research, 1995
- A comparison of thein vitroactivity of DNA-armed and all-RNA hammerhead ribozymesNucleic Acids Research, 1995
- CONTROL OF RNA INITIATION AND ELONGATION AT THE HIV-1 PROMOTERAnnual Review of Biochemistry, 1994
- Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication—potential effectiveness against most presently sequenced HIV-1 isolatesNucleic Acids Research, 1992
- Simple RNA enzymes with new and highly specific endoribonuclease activitiesNature, 1988
- The Chemistry of Self-Splicing RNA and RNA EnzymesScience, 1987