Potassium and Creatinine as Indexes of Muscle and Nonmuscle Protein in Rats

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Abstract
Rate of creatinine formation in vivo was studied in 29 albino rats (12 full-fed males, 10 restricted-fed males and 7 full-fed females) ranging in age from 81 to 188 days. Equations for predicting the quantities of muscle, nonmuscle and total body protein were formulated by using total body potassium and 24-hour urinary creatinine excretion. Predicted values of muscle, nonmuscle and total body protein agree with the gravimetrically determined values within ± 4.17%, ± 7.50% and ± 3.41%, respectively, in rat carcasses.