HUMAN PLACENTAL-LACTOGEN - PREDICTOR OF PERINATAL OUTCOME

  • 1 January 1979
    • journal article
    • research article
    • Vol. 54  (2) , 205-210
Abstract
Serial human placental lactogen (hPL) determinations were performed on 806 women with normal and abnormal pregnancies late in the pregnancy. These results were not reported to the clinicians involved. For the study population as a whole, low hPL levels did not effectively predict those adverse perinatal outcome variables evaluated. Further analysis revealed that this was true both for the normal and abnormal pregnancy groups. The routine use of antepartum hPL screening, as advocated by others, as a means of improving perinatal outcome is not supported. In certain at-risk patients, there was an association between low hPL values and the presence of 1 or more of the adverse outcome variables. These patients were recognized clinically as having fetuses in jeopardy.

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