Microwave-Accelerated SPOT-Synthesis on Cellulose Supports
- 18 May 2004
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 6 (12) , 2019-2022
- https://doi.org/10.1021/ol049313f
Abstract
We demonstrate that microwave irradiation can dramatically accelerate reaction rates for spatially addressable library synthesis on planar membrane supports. The development of a robust support/linker system, microwave-assisted synthesis of small molecule test libraries, and methods for solid-phase scale-up on cellulose are described.Keywords
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