Differential changes in Cu, Zn and Mn superoxide dismutase activity in developing rat brain and liver
- 1 July 1990
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 46 (7) , 753-755
- https://doi.org/10.1007/bf01939957
Abstract
The aim of our study was to assess the pattern of copper and zinc-containing superoxide dismutase (Cu, ZnSOD) and manganese-containing superoxide dismutase (MnSOD) activity from embryonic life to senescence in rat brain and liver. The two isoenzymes showed different profiles in the two organs examined. In particular, the cerebral MnSOD activity profile suggests a primary role during differentiation of this enzymatic form.This publication has 16 references indexed in Scilit:
- Effects of Methylprednisolone and the Combination of α‐Tocopherol and Selenium on Arachidonic Acid Metabolism and Lipid Peroxidation in Traumatized Spinal Cord TissueJournal of Neurochemistry, 1987
- Regional Distributions of Thiobarbituric Acid‐Reactive Products, Activities of Enzymes Regulating the Metabolism of Oxygen Free Radicals, and Some of the Related Enzymes in Adult and Aged Rat BrainsJournal of Neurochemistry, 1986
- Relationship between oxygen metabolism, aging and developmentAdvances in Free Radical Biology & Medicine, 1986
- Relationship between Metabolic Rate, Free Radicals, Differentiation and Aging: A Unified TheoryPublished by Springer Nature ,1985
- The role of superoxide dismutase and gene amplification in carcinogenesisJournal of Theoretical Biology, 1984
- [61] Assay of superoxide dismutase activity in tumor tissuePublished by Elsevier ,1984
- A two-step hypothesis on the mechanisms of in vitro cell aging: Cell differentiation followed by intrinsic mitochondrial mutagenesisExperimental Gerontology, 1984
- The aging process.Proceedings of the National Academy of Sciences, 1981
- Enzyme levels of normal human cells: Aging in cultureArchives of Biochemistry and Biophysics, 1975
- Superoxide dismutase: Improved assays and an assay applicable to acrylamide gelsAnalytical Biochemistry, 1971