Asymmetric synthesis of α-amino-acid derivatives by alkylation of a chiral Schiff base

1 January 1976

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 4,p. 136-137
https://doi.org/10.1039/c39760000136

Abstract

An efficient asymmetric synthesis of D-α-amino-acid derivatives has been achieved by alkylation of a Schiff base prepared from glycine t-butyl ester and (1S,2S,5S)-2-hydroxypinan-3-one.

Keywords

ASYMMETRIC SYNTHESIS
AMINO ACID