Ear Wax and Host Defense

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Abstract
The means by which the body defends itself against surface invaders has engaged the curiosity of generations of microbiologists and immunologists; the history of lysozyme is a singular example. Fleming's discovery of a substance in his nasal mucus capable of lysing colonies of certain environmental bacteria led him and others to a successful search for similar activity in egg white as well as in a variety of mammalian secretions. Its analogues were later detected in nearly all living things, ranging from bacteriophages to lysosomal granules of phagocytic cells. Within the past decade the primary amino acid sequences of representative lysozymes . . .