INHIBITION BY AMILORIDE OF SODIUM‐DEPENDENT FLUID REABSORPTION IN THE RAT ISOLATED CAUDAL EPIDIDYMIS
Open Access
- 1 December 1976
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 58 (4) , 529-531
- https://doi.org/10.1111/j.1476-5381.1976.tb08620.x
Abstract
The rate of fluid reabsorption was studied in the rat isolated caudal epididymal sac in vitro. Part of the fluid reabsorption was found to be dependent on intraluminal Na+. Amiloride (0.1 mm) completely inhibited this component of fluid reabsorption. The log dose‐inhibition curve to amiloride was sigmoid and the IC50 value was found to be 1.6 μm.Keywords
This publication has 4 references indexed in Scilit:
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