Blunted Prefrontal Cortical 18Fluorodeoxyglucose Positron Emission Tomography Response to Meta-Chlorophenylpiperazine in Impulsive Aggression
Open Access
- 1 July 2002
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 59 (7) , 621-629
- https://doi.org/10.1001/archpsyc.59.7.621
Abstract
ALTHOUGH VIOLENT crime has decreased in the past decade, violent incidents involving impulsive aggression rather than planned violence are increasing.1 These include juvenile violence, domestic violence, and workplace acts of aggression.2,3 Violence and homicide are significantly associated with mental illness, especially antisocial and borderline personality disorder.4 Considering the serious consequences of impulsive-aggressive behavior, its neurobiology has received little scrutiny.Keywords
This publication has 32 references indexed in Scilit:
- Help-seeking for intimate partner violence and forced sex in South CarolinaAmerican Journal of Preventive Medicine, 2000
- Dysfunction in the Neural Circuitry of Emotion Regulation--A Possible Prelude to ViolenceScience, 2000
- Cognitive and emotional influences in anterior cingulate cortexTrends in Cognitive Sciences, 2000
- Impairment of social and moral behavior related to early damage in human prefrontal cortexNature Neuroscience, 1999
- Hormonal responses to meta-chlorophenylpiperazine (m-CPP) are undiminished by acute m-CPP pretreatmentPsychiatry Research, 1996
- Physiological responses to d-fenfluramine and ipsapirone challenge correlate with indices of aggression in males with personality disorderInternational Clinical Psychopharmacology, 1995
- Frontal-subcortical circuits and neuropsychiatric disordersThe Journal of Neuropsychiatry and Clinical Neurosciences, 1994
- The Return of Phineas Gage: Clues About the Brain from the Skull of a Famous PatientScience, 1994
- An approach to the neurology of aggressionJournal of Psychiatric Research, 1988
- Effects of orbital frontal lesions on aversive and aggressive behaviors in rhesus monkeys.Journal of Comparative and Physiological Psychology, 1970