Why Does a Pseudohermaphrodite Want to Be a Man?

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To the Editor: Research demonstrating that androgens affect the developing brain of rodents, determining subsequent cyclical gonadotropin production and influencing adult mating and fighting behavior, has, for decades, been recklessly extrapolated to interpretations of primate and human behavior despite evidence that the rodent model does not apply to primates or humans. That the assumptions derived from the work on rodents can seriously affect the scientific objectivity and methodology of investigators is evident in the article in the Journal 1 that claims to demonstrate that exposure of the brain to testosterone in utero was the critical factor in determining subsequent male gender . . .