Production of Renin by Constricting Renal Artery of an Isolated Kidney Perfused with Blood

Abstract
Renin appears to be produced by normal isolated dog's kidney perfused with blood when pulse pressure and blood flow are reduced by constricting the renal artery. Reduction of mean pressure is not a necessary condition. It is not produced when the hind leg is perfused under similar circumstances nor by kidneys perfused by blood under normal pressure-flow conditions.

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