Transfer RNA Biosynthesis: The Nucleotide Sequence of a Precursor to Serine and Proline Transfer RNAs
- 1 February 1974
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 71 (2) , 413-416
- https://doi.org/10.1073/pnas.71.2.413
Abstract
The nucleotide sequence of a transfer RNA precursor molecule coded by bacteriophage T4 has been determined. The molecule is a single polynucleotide chain which contains two transfer RNA species that are destined to recognize serine and proline. The 3' -CCA(OH) termini of both mature transfer RNA species are absent in the precursor molecule; these termini must therefore be added enzymatically at a subsequent stage of maturation. Nucleotide residues unique to the precursor are located at both ends of the molecule and between the two transfer RNA sequences.Keywords
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