Bacteriological Investigation on an Outbreak of Acute Enteritis associated with Verotoxin-producing Escherichia coli O111: H-
- 1 January 1989
- journal article
- abstracts
- Published by The Japanese Association for Infectious Diseases in Kansenshogaku Zasshi
- Vol. 63 (10) , 1187-1194
- https://doi.org/10.11150/kansenshogakuzasshi1970.63.1187
Abstract
An outbreak of acute enteritis in children aged one to thirty-three months occurred from June 10th to 23rd, 1986, at a private orphanage in Matsuyama City. Twenty-two out of 23 children suffered from diarrhea. Nine of the 22 children excreted bloody stool. Fever and vomiting were observed with a few patients. One of them, a 33-month-old girl, developed hemolytic uremic syndrome, and died twelve days after the admission. Escherichia coli O111:H- was isolated from fecal specimens of 7 out of 15 patients. The culture filtrate of the isolate caused fluid accumulation in ligated ileal loops in a rabbit, and was lethal to mice. It was found that all isolates produced two kinds of Vero toxins (VT1 and VT2, or shiga-like toxin I and II). The amount of VT2 produced in vitro was about 10 times more than that of VT1.Keywords
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