Preparation of coated-wire potentiometric enzyme sensors.

Abstract
A silver/silver chloride (Ag/AgCl) electrode coated with a tri-n-dodecylamine/poly(vinyl chloride) composite membrane was used to make potentiometric enzyme sensors. When the pH-sensitive membrane-coated Ag/AgCl electrode was further coated with a urease or penicillinase membrane, it responded potentiometrically to urea and penicillin. The performance of the enzyme sensors was comparable to conventional enzyme sensors.