Two unusual, striking, and puzzling cases of persistent denudation of the scalp have been followed for 5 and 10 years respectively by 2 of us (A. H. S. and J. W. B.). The first patient was presented before the Chicago Dermatological Society in February, 1955, as: "A Case for Diagnosis— Pemphigus Vulgaris?"1 This led to the comparative study of the second such extraordinary clinical manifestation. The diagnosis of pemphigus is often made only after enough time has elapsed to complete the characteristic picture. Senear2 has pointed out the effectiveness of certain well-accepted criteria for diagnosis in certain cases. When the disorders of the pemphigoid group are added to the differential problem, however, the dilemma becomes compounded. The present report concerns 2 cases of cicatricial pemphigoid. Both patients displayed massive nonhealing erosive lesions affecting the major portions of the scalp. Report of Cases Case 1.— A 56-year-old white woman