Antidiuretic Hormone Values in Plasma and Urine of Malnourished Children

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Abstract
The contribution of antidiuretic hormone (ADH) to the development of edema in protein calorie malnutrition was investigated ADH levels in plasma and in urine were determined in children suffering from kwashiorkor both at the edematous stage and after the disappearance of edema following treatment. ADH levels were also determined in some children suffering from marasmus who were grossly malnourished but did not have edema. Plasma and urine ADH levels in children with kwashiorkor were significantly higher than those in normal or marasmic children. Following therapy and disappearance of edema, levels of the hormone had returned to normal both in plasma and in urine, in children with kwashiorkor. These results suggest that high ADH levels are associated with the edema in protein calorie malnutrition.

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