SEROTYPING OF HUMAN ROTAVIRUS BY ENZYME IMMUNO-ASSAY WITH MONOCLONAL ANTIBODIES
- 1 January 1993
- journal article
- research article
- Published by Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis in Japanese Journal of Medical Science and Biology
- Vol. 46 (5-6) , 221-226
- https://doi.org/10.7883/yoken1952.46.221
Abstract
Two series of enzyme immunoassays with monoclonal antibodies produced in two laboratories (A and B) were compared in use for serotyping of human rotavirus in stool samples collected in Japan between 1988 and 1991 from patients with gastroenteritis. Of 358 samples, 222 were determined to be the same serotype, while 61 samples could not be serotyped by either assay. A hundred and one and 92 samples were not serotyped by the A and B antibodies, respectively. We believe that the A and B monoclonal antibodies are useful clinically for serotyping rotaviruses at the present time.Keywords
This publication has 4 references indexed in Scilit:
- Antigenic and Genetic Analyses of Human Rotaviruses in Chiang Mai, Thailand: Evidence for a Close Relationship between Human and Animal RotavirusesThe Journal of Infectious Diseases, 1992
- Epidemiology of Rotavirus Infection Around Tokyo AreaKansenshogaku Zasshi, 1989
- Validity of an Enzyme-Linked Immunosorbent Assay with Serotype-Specific Monoclonal Antibodies for Serotyping Human Rotavirus in Stool SpecimensMicrobiology and Immunology, 1988
- Direct Serotyping of Human Rotavirus in Stools by an Enzyme-Linked Immunosorbent Assay Using Serotype 1-, 2-, 3-, and 4-Specific Monoclonal Antibodies to VP7The Journal of Infectious Diseases, 1987