Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat
- 29 June 2005
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 182 (1) , 180-185
- https://doi.org/10.1007/s00213-005-0059-7
Abstract
It has been reported that each of three drugs effective in treating bipolar disorder (lithium, carbamazepine, and valproate) decreases the turnover of arachidonic acid (AA, 20:4n-6) in brain phospholipids of the awake rat. It is also known that lithium and carbamazepine do so without decreasing the turnover of docosahexaenoic acid (DHA, 22:6n-3).Keywords
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