Modification of (S)-N,N-Dimethyl-1-[(R)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine (BPPFA) as a Ligand for Asymmetric Hydrogenation of Olefins Catalyzed by a Chiral Rhodium(I) Complex

Abstract
Asymmetric homogeneous hydrogenation of prochiral olefins catalyzed by chiral rhodium(I) complexes was carried out by using several ferrocenylphosphines as ligands which play a key role of the chiral recognition. Modifications of BPPFA were made in order to examine a steric effect of the given substutient at the asymmetric center on the efficiency of the chiral ligands, indicating the parent BPPFA to be superior to the others examined for the asymmetric hydrogenation of highly functionalized olefins.

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