ALPHA-CHAIN DISEASE WITH LOCALIZED PLASMACYTOMA OF INTESTINE - IMMUNOPEROXIDASE STUDY

  • 1 January 1976
    • journal article
    • research article
    • Vol. 25  (1) , 112-116
Abstract
An ileocecal tumor in a patient with .alpha.-chain disease in remission was studied immunohistochemically by a quantitative immunoperoxidase method. The tumor which was histologically shown to be a plasmacytoma, consisted of 68% .alpha. cells and 15% .lambda. cells; no .kappa. cells were found. Away from the tumor the pattern of immunoglobulin-producing cells was normal. The abnormal cell causing .alpha.-chain disease remains inactive; the patient developed a plasmacytoma from a different cell clone.